Semax

Semax – 10 mg / 20 mg

For In Vitro Research Use Only
Not for Human or Veterinary Application

Product Overview

Semax is a synthetic heptapeptide analog of the adrenocorticotropic hormone fragment ACTH(4-7), with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. It was developed as a research tool for studying neurotrophin regulation and neuroprotective signaling mechanisms in central nervous system cell models. Semax is studied in the context of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) expression modulation, melanocortin receptor subtype signaling, and ischemia-related neuronal stress responses in preclinical research settings.

Specifications

• Quantity: 10 mg / 20 mg

• Form: Lyophilized Powder

• Sequence: Met-Glu-His-Phe-Pro-Gly-Pro

• CAS: 80714-61-0

• Molecular Weight: 813.9 Da

• Purity: ≥99.4% (third-party verified)

• Storage: -20°C long-term; 4°C short-term (use within 4 weeks of reconstitution)

Research Context

Semax is structurally derived from the ACTH(4-7) core sequence, which interacts with melanocortin receptors (MC2R, MC4R) expressed in neural tissue, and its Pro-Gly-Pro C-terminal extension is associated with resistance to enzymatic degradation and enhanced central nervous system penetration in animal models. Research involving Semax has examined upregulation of BDNF and NGF mRNA expression in hippocampal and cortical cell preparations, as well as modulation of the tissue plasminogen activator (tPA) system and serotonergic signaling in neuronal assay contexts. It is studied in the context of oxidative stress responses, neuroinflammation, and excitotoxicity models using in vitro neuronal cultures. Semax has also been researched for its effects on nitric oxide synthesis and cerebrovascular regulatory pathways in endothelial-neuronal co-culture systems.

Intended Use

This compound is intended strictly for in vitro laboratory research by qualified professionals.
It is not approved for:

• Human use

• Veterinary use

• Food, drug, diagnostic, or cosmetic applications

Regulatory Disclaimer

• This compound has not been evaluated by the U.S. Food and Drug Administration (FDA).

• It is not intended to diagnose, treat, cure, or prevent any disease.

• All handling and use must comply with applicable institutional, local, state, and federal regulations.

Terms of Sale

By purchasing from Axis Peptide Labs, the buyer confirms that they are a qualified researcher, laboratory, or institution and acknowledge that the product is for research use only.

• All sales are final.

• The purchaser assumes full responsibility for compliant handling, storage, and use.

• Resale for human consumption is strictly prohibited.