MOTS-C

MOTS-c – 10 mg

For In Vitro Research Use Only
Not for Human or Veterinary Application

Product Overview

MOTS-c is a 16-amino acid peptide encoded within the 12S ribosomal RNA region of the mitochondrial genome, one of the class of mitochondrial-derived peptides (MDPs). It is used as a research tool for studying AMP-activated protein kinase (AMPK) pathway activation and mitochondrial-nuclear signaling in cell-based models.

Specifications

• Quantity: 10 mg

• Form: Lyophilized Powder

• Sequence: MRWQEMGYIFYPRKLR

• Molecular Formula: C101H152N28O22S2

• CAS: 1627580-64-6

• Molecular Weight: 2,174.6 Da

• Purity: Printed on the lot certificate

• Storage: -20°C long-term; 4°C short-term (use within 4 weeks of reconstitution)

Research Context

MOTS-c has been studied in the context of AMPK activation through the AICAR/ZMP pathway, in which it inhibits the folate cycle and de novo purine synthesis, leading to AICAR accumulation and AMPK phosphorylation. Published research has also examined its nuclear translocation under oxidative stress and its interaction with the Nrf2 antioxidant response pathway in vitro.

Certificate of Analysis

Every lot is tested by an independent laboratory. The certificate for this product is shown on this page and on the Test Results page.

Intended Use

This compound is intended strictly for in vitro laboratory research by qualified professionals. It is not a drug, food, or cosmetic and is not approved for:

• Human use

• Veterinary use

• Food, drug, diagnostic, or cosmetic applications

Regulatory Disclaimer

• This compound has not been evaluated by the U.S. Food and Drug Administration (FDA). It is not intended to diagnose, treat, cure, or prevent any disease.

• It is sold strictly as a research material with no medical or therapeutic claims.

• All handling and use must comply with applicable institutional, local, state, and federal regulations.

Terms of Sale

By purchasing from Axis Peptide Labs, the buyer confirms that they are a qualified researcher, laboratory, or institution and acknowledge that the product is for research use only.

• The purchaser assumes full responsibility for compliant handling, storage, and use.

• Resale for human consumption is strictly prohibited.