Sermorelin and CJC-1295 are both GHRH-based growth hormone secretagogues. The main difference is duration: CJC-1295 is engineered to be longer-acting than Sermorelin. Both are supplied for research use only.
Side by side
| Sermorelin | CJC-1295 | |
|---|---|---|
| Based on | A GHRH fragment | A GHRH analog |
| Class | GH secretagogue | GH secretagogue |
| Duration | Shorter-acting | Longer-acting |
| Status | Research use only | Research use only |

Same family, different duration
Both peptides work from the same starting point, GHRH, and belong to the same secretagogue family. The practical distinction most often discussed is duration of action: CJC-1295 carries modifications intended to make it longer-acting, while Sermorelin is shorter-acting.
Browse research-grade peptides
Every Axis compound is third-party tested to 99.4%+ purity, with a certificate of analysis on every batch.
What to look for
Whichever you study, a research-grade compound should ship with a batch-specific certificate of analysis. CJC-1295 is also frequently studied with Ipamorelin.
Key takeaways
- Sermorelin and CJC-1295 are both GHRH-based secretagogues.
- The main difference is duration of action.
- CJC-1295 is engineered to be longer-acting.
- Both are research compounds, supplied for research use only.
A note on research use
The peptides supplied by Axis Peptide Labs are reference compounds for laboratory and research use only. They are intended for qualified researchers working in academic, institutional, and analytical settings. They are not drugs, foods, cosmetics, or medical products, and they are not intended for human or veterinary consumption. Documented identity and documented purity are what matter most when sourcing a compound, both of which are published on the Axis certificates of analysis page.
